A tert-butyldimethylsilylating agent.The t-butyldimethylsilyl group is relatively stable against deblocking in weakly acidic or basic media and mild oxidizing and reducing conditions. Extensively used in terpenoid and carbohydrate chemistry.1,2 Also used in the protection of alcohols, amines, carboxylic acids, phenols and other substrate.3
1. BioResources 2008, 3, 79.
2. Chem. Pharm. Bull. 2001, 49, 1644.
3. Phosphorus, Sulfur Silicon Relat. Elem. 1998, 143, 45.