Convenient form of anhydrous HF, showing increased reactivity in many reactions. Has been used for the preparation of β-fluoroamines from amino alcohols and for the fluorination of acetylenes,1,2 electrophilic electrochemical fluorination 3 and conversion of carboxylic acids to acyl fluorides.4 Used together with hypervalent iodine(III) reagents for ipso-fluorination of para-substituted phenols providing cyclohexadienones.5 Employed with Selectfluor™ for geminal fluorination of 2,2-diaryl-1,3-dithiolanes.6
1. J. Fluor. Chem. 1987, 37, 343.
2. Tetrahedron Lett. 1991, 32, 69.
3. J. Fluorine Chem. 1997, 83, 31.
4. J. Fluorine Chem. 2002, 115, 75.
5. Tetrahedron 2004, 60, 6629.
6. Chem. Commun. 2005, 654.